Recombinant humaan sFRP-5/SFRP5 eiwit

SARP3, also known as secreted frizzled-related protein 5, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. Recombinant SFRP5, fused to His-tag at N-terminus, was expressed in E. coli.

Secreted frizzled-related protein 5, sFRP-5, Frizzled-related protein 1b, FRP-1b, Secreted apoptosis-related protein 3, SARP-3

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

35 kDa (311aa)

SFRP5, Secreted frizzled-related protein 5, SARP3, ATGP2966-10 µg, ATGP2966-20 µg, ATGP2966-50 µg, ATGP2966-100 µg, ATGP2966-250 µg, ATGP2966-500 µg, ATGP2966-1 mg, ATGP2966-10, ATGP2966-20, ATGP2966-50, ATGP2966-100, ATGP2966-250, ATGP2966-500, ATGP2966-1

Veeck J, Geisler C, et al. (2008) . Carcinogenesis. 29 (5) :991-8.; ; urakami S, Shiina H, et al. (2006) . Clin Cancer Res. 12 (7 Pt 1) :2109-16.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Stem cell

NP_003006

Q5T4F7

Human

EEYDYYG WQAEPLHGRS YSKPPQCLDI PADLPLCHTV GYKRMRLPNL LEHESLAEVK QQASSWLPLL AKRCHSDTQV FLCSLFAPVC LDRPIYPCRS LCEAVRAGCA PLMEAYGFPW PEMLHCHKFP LDNDLCIAVQ FGHLPATAPP VTKICAQCEM EHSADGLMEQ MCSSDFVVKM RIKEIKIENG DRKLIGAQKK KKLLKPGPLK RKDTKRLVLH MKNGAGCPCP QLDSLAGSFL VMGRKVDGQL LLMAVYRWDK KNKEMKFAVK FMFSYPCSLY YPFFYGAAEP H