Recombinant humaan SFRS1-eiwit

Serine/arginine-rich splicing factor 1, also known as SFRS1, is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. This protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Recombinant human SFRS1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Serine/arginine-rich splicing factor 1, ASF, MGC5228, SF2, SF2p33, SRp30a

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

29.9 kDa (268aa)

SFRS1, Serine/arginine-rich splicing factor 1, ASF, MGC5228, SF2, SF2p33, SRp30a, ATGP1949-10 µg, ATGP1949-20 µg, ATGP1949-50 µg, ATGP1949-100 µg, ATGP1949-250 µg, ATGP1949-500 µg, ATGP1949-1 mg, ATGP1949-10, ATGP1949-20, ATGP1949-50, ATGP1949-100, ATGP1949-250, ATGP1949-500, ATGP1949-1

Zuo P., et al. (1993) EMBO J. 12:4727-4737; ; Kohtz J.D., et al. (1994) Nature. 368:119-124;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Epigenomics (Transcription & Translation)

NP_008855

Q07955

Human

MGSSHHHHHH SSGLVPRGSH MSGGGVIRGP AGNNDCRIYV GNLPPDIRTK DIEDVFYKYG AIRDIDLKNR RGGPPFAFVE FEDPRDAEDA VYGRDGYDYD GYRLRVEFPR SGRGTGRGGG GGGGGGAPRG RYGPPSRRSE NRVVVSGLPP SGSWQDLKDH MREAGDVCYA DVYRDGTGVV EFVRKEDMTY AVRKLDNTKF RSHEGETAYI RVKVDGPRSP SYGRSRSRSR SRSRSRSRSN SRSRSYSPRR SRGSPRYSPR HSRSRSRT