Recombinant humaan SH2D1B-eiwit

SH2D1B, also known as SH2 domain-containing protein 1B, is one of the proteins which activate NK cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. Two isoforms of the human protein are produced by alternative splicing. Recombinant human SH2D1B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

SH2 domain-containing protein 1B, SH2D1B, EAT2

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

16.4 kDa (141aa)

SH2D1B, ATGP3657-10 µg, ATGP3657-20 µg, ATGP3657-50 µg, ATGP3657-100 µg, ATGP3657-250 µg, ATGP3657-500 µg, ATGP3657-1 mg, ATGP3657-10, ATGP3657-20, ATGP3657-50, ATGP3657-100, ATGP3657-250, ATGP3657-500, ATGP3657-1

Perez-Quintero LA., et al, (2014) J Exp Med. 211:727-742.; ; Aldhamen YA., et al, (2012) J Immunol. 189:1349-1359.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Immunology

NP_444512.2

O14796

Human

Ala

MDLPYYH GRLTKQDCET LLLKEGVDGN FLLRDSESIP GVLCLCVSFK NIVYTYRIFR EKHGYYRIQT AEGSPKQVFP SLKELISKFE KPNQGMVVHL LKPIKRTSPS LRWRGLKLEL ETFVNSNSDY VDVLP