Recombinant humaan Siglec-5 eiwit

SIGLEC5, also known as sialic acid-binding Ig-like lectin 5, belongs to immunoglobulin superfamily and SIGLEC family. This protein is composed of 2 Ig-like C2-type domains and 1 Ig-like V-type domain. Also, it is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, and at lower levels in lymph node, appendix, pancreas, lung, and thymus. Recombinant human SIGLEC5, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Sialic acid-binding Ig-like lectin 5, SIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

74.2 kDa (667aa)

Siglec5, Sialic acid-binding Ig-like lectin 5, SIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5, ATGP3601-10 µg, ATGP3601-20 µg, ATGP3601-50 µg, ATGP3601-100 µg, ATGP3601-250 µg, ATGP3601-500 µg, ATGP3601-1 mg, ATGP3601-10, ATGP3601-20, ATGP3601-50, ATGP3601-100, ATGP3601-250, ATGP3601-500, ATGP3601-1

Fong JJ., et al, (2015) EMBO J. 34:2775-2788.; ; Ali SR., et al, (2014) J. Exp. Med. 211:1231-1242.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Immunology

NP_003821

O15389

Human

Ala

EKPVYEL QVQKSVTVQE GLCVLVPCSF SYPWRSWYSS PPLYVYWFRD GEIPYYAEVV ATNNPDRRVK PETQGRFRLL GDVQKKNCSL SIGDARMEDT GSYFFRVERG RDVKYSYQQN KLNLEVTALI EKPDIHFLEP LESGRPTRLS CSLPGSCEAG PPLTFSWTGN ALSPLDPETT RSSELTLTPR PEDHGTNLTC QMKRQGAQVT TERTVQLNVS YAPQTITIFR NGIALEILQN TSYLPVLEGQ ALRLLCDAPS NPPAHLSWFQ GSPALNATPI SNTGILELRR VRSAEEGGFT CRAQHPLGFL QIFLNLSVYS LPQLLGPSCS WEAEGLHCRC SFRARPAPSL CWRLEEKPLE GNSSQGSFKV NSSSAGPWAN SSLILHGGLS SDLKVSCKAW NIYGSQSGSV LLLQGRSNLG TGVVPAAL