Recombinant humaan Siglec-6/CD327 eiwit

SIGLEC6, also known as sialic acid-binding Ig-like lectin 6 isoform 1, is one of immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. It mediates sialic-acid dependent binding to cells and binds to alpha-2, 6-linked sialic acid. This protein localizes in various compartments such as membrane fraction, extracellular region and so on. Recombinant human SIGLEC6 protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Sialic acid-binding Ig-like lectin 6 isoform 1, SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

62.6 kDa (563aa)

Siglec6, CD327, Sialic acid-binding Ig-like lectin 6 isoform 1, SIGLEC6, CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1, ATGP3628-10 µg, ATGP3628-20 µg, ATGP3628-50 µg, ATGP3628-100 µg, ATGP3628-250 µg, ATGP3628-500 µg, ATGP3628-1 mg, ATGP3628-10, ATGP3628-20, ATGP3628-50, ATGP3628-100, ATGP3628-250, ATGP3628-500, ATGP3628-1

Lam KK., et al, (2011) J Biol Chem. 286:37118-37127.; ; Rumer KK., et al, (2013) Reprod Sci. 20:646-53.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_001236

O43699

Human

Ala

QERRFQL EGPESLTVQE GLCVLVPCRL PTTLPASYYG YGYWFLEGAD VPVATNDPDE EVQEETRGRF HLLWDPRRKN CSLSIRDARR RDNAAYFFRL KSKWMKYGYT SSKLSVRVMA LTHRPNISIP GTLESGHPSN LTCSVPWVCE QGTPPIFSWM SAAPTSLGPR TTQSSVLTIT PRPQDHSTNL TCQVTFPGAG VTMERTIQLN VSYAPQKVAI SIFQGNSAAF KILQNTSSLP VLEGQALRLL CDADGNPPAH LSWFQGFPAL NATPISNTGV LELPQVGSAE EGDFTCRAQH PLGSLQISLS LFVHWKPEGR AGGV