Recombinant humaan Siglec-9 eiwit

SIGLEC9, also known as sialic acid-binding Ig-like lectin 9 isoform 1, is a novel member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF) expressed broadly on human blood leukocytes. It has a high-level expression in bone marrow, placenta, spleen, and fetal liver. It is a member of the recently characterized CD33-related Siglec family of sialic acid binding protein and is expressed on human monocytes and NK cells. Recombinant human SIGLEC9, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Sialic acid-binding Ig-like lectin 9 isoform 1, SIGLEC9, CD329, CDw329, FOAP-9, OBBP-LIKE

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

63.3 kDa (573aa)

Siglec9, ATGP3622-10 µg, ATGP3622-20 µg, ATGP3622-50 µg, ATGP3622-100 µg, ATGP3622-250 µg, ATGP3622-500 µg, ATGP3622-1 mg, ATGP3622-10, ATGP3622-20, ATGP3622-50, ATGP3622-100, ATGP3622-250, ATGP3622-500, ATGP3622-1

Avril T., et al. (2004) J Immunol. 173:6841-6849.; ; Zhang JQ., et al. (2000) J Biol Chem. 275:22121-22126.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_001185487

Q9Y336

Human

Ala

QTSKLLT MQSSVTVQEG LCVHVPCSFS YPSHGWIYPG PVVHGYWFRE GANTDQDAPV ATNNPARAVW EETRDRFHLL GDPHTKNCTL SIRDARRSDA GRYFFRMEKG SIKWNYKHHR LSVNVTALTH RPNILIPGTL ESGCPQNLTC SVPWACEQGT PPMISWIGTS VSPLDPSTTR SSVLTLIPQP QDHGTSLTCQ VTFPGASVTT NKTVHLNVSY PPQNLTMTVF QGDGTVSTVL GNGSSLSLPE GQSLRLVCAV DAVDSNPPAR LSLSWRGLTL CPSQPSNPGV LELPWVHLRD AAEFTCRAQN PLGSQQVYLN VSLQSKATSG VTQG