Recombinant humaan SIRP gamma/CD172g eiwit

SIRPG is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. Recombinant human SIRPG protein, fused to His-tag at N-terminus, was expressed in E. coli.

Signal-regulatory protein gamma isoform 1 precursor, bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

39.1 kDa (355aa)

SIRP g, CD172g, signal-regulatory protein gamma isoform 1 precursor, bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma, ATGP2747-10 µg, ATGP2747-20 µg, ATGP2747-50 µg, ATGP2747-100 µg, ATGP2747-250 µg, ATGP2747-500 µg, ATGP2747-1 mg, ATGP2747-10, ATGP2747-20, ATGP2747-50, ATGP2747-100, ATGP2747-250, ATGP2747-500, ATGP2747-1

Piccio L., et al (2005) . Blood 105:2421-2427; ; Ichigotani Y., et al (2000) . J. Hum. Genet. 45:378-382;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Immunology

NP_061026

Q9P1W8

Human

MGSSHHHHHH SSGLVPRGSH MGSEEELQMI QPEKLLLVTV GKTATLHCTV TSLLPVGPVL WFRGVGPGRE LIYNQKEGHF PRVTTVSDLT KRNNMDFSIR ISSITPADVG TYYCVKFRKG SPENVEFKSG PGTEMALGAK PSAPVVLGPA ARTTPEHTVS FTCESHGFSP RDITLKWFKN GNELSDFQTN VDPTGQSVAY SIRSTARVVL DPWDVRSQVI CEVAHVTLQG DPLRGTANLS EAIRVPPTLE VTQQPMRVGN QVNVTCQVRK FYPQSLQLTW SENGNVCQRE TASTLTENKD GTYNWTSWFL VNISDQRDDV VLTCQVKHDG QLAVSKRLAL EVTVHQKDQS SDATP