Recombinant humaan SIX1-eiwit

SIX1, also known as homeobox protein SIX1, is a member of the SIX gene family. It encodes protein that is characterized by a divergent DNA-binding homeodomain and an upstream SIX domain, which may be involved both in determining DNA-binding specificity and in mediating protein-protein interactions. It has been shown to play roles in vertebrate and insect development or has been implicated in maintenance of the differentiated state of tissues. Recombinant human SIX1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Homeobox protein SIX1, BOS3, DFNA23, TIP39

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

34.7 kDa (308aa)

SIX1, homeobox protein SIX1, BOS3, DFNA23, TIP39, ATGP1728-10 µg, ATGP1728-20 µg, ATGP1728-50 µg, ATGP1728-100 µg, ATGP1728-250 µg, ATGP1728-500 µg, ATGP1728-1 mg, ATGP1728-10, ATGP1728-20, ATGP1728-50, ATGP1728-100, ATGP1728-250, ATGP1728-500, ATGP1728-1

Ruf RG. et al. (2004) Proc Natl Acad Sci u S A. 101 (21) :8090-8095.; ; Oliver G. et al. (1995) Development. 121 (3) :693-705.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea

Epigenomics (Transcription & Translation)

NP_005973

Q15475

Human

MGSSHHHHHH SSGLVPRGSH MGSHMSMLPS FGFTQEQVAC VCEVLQQGGN LERLGRFLWS LPACDHLHKN ESVLKAKAVV AFHRGNFREL YKILESHQFS PHNHPKLQQL WLKAHYVEAE KLRGRPLGAV GKYRVRRKFP LPRTIWDGEE TSYCFKEKSR GVLREWYAHN PYPSPREKRE LAEATGLTTT QVSNWFKNRR QRDRAAEAKE RENTENNNSS SNKQNQLSPL EGGKPLMSSS EEEFSPPQSP DQNSVLLLQG NMGHARSSNY SLPGLTASQP SHGLQTHQHQ LQDSLLGPLT SSLVDLGS