Recombinant humaan SNRPB2-eiwit

SNRPB2, also known as u2 small nuclear ribonucleoprotein B, belongs to the RRM u1 A/B family. This protein associates with stem loop IV of u2 small nuclear ribonucleoprotein (u2 snRNP) in the presence of snRNP-A. It may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. Recombinant human SNRPB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

U2 small nuclear ribonucleoprotein B, u2 snRNP B

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

27.6 kDa (245aa) confirmed by MALDI-TOF

SNRPB2, u2 small nuclear ribonucleoprotein B, u2 snRNP B, ATGP1044-10 µg, ATGP1044-20 µg, ATGP1044-50 µg, ATGP1044-100 µg, ATGP1044-250 µg, ATGP1044-500 µg, ATGP1044-1 mg, ATGP1044-10, ATGP1044-20, ATGP1044-50, ATGP1044-100, ATGP1044-250, ATGP1044-500, ATGP1044-1

Guo JX., et al. (2001) Biophys J. 81 (2) :630-42; ; Price S.R., et al. (1998) Nature.394:645-650

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.1M NaCl

Immunology

NP_003083

P08579

Human

MDIRPNHTIY INNMNDKIKK EELKRSLYAL FSQFGHVVDI VALKTMKMRG QAFVIFKELG SSTNALRQLQ GFPFYGKPMR IQYAKTDSDI ISKMRGTFAD KEKKKEKKKA KTVEQTATTT NKKPGQGTPN SANTQGNSTP NPQVPDYPPN YILFLNNLPE ETNEMMLSML FNQFPGFKEV RLVPGRHDIA FVEFENDGQA GAARDALQGF KITPSHAMKI TYAKK