Recombinant humaan SNRPC-eiwit

SNRPC belongs to the u1 small nuclear ribonucleoprotein C family. This protein component of the u1 small nuclear ribonucleoprotein (snRNP) particle required for the formation of the spliceosome. This protein participates in the processing of nuclear precursor messenger RNA splicing. snRNP particles are attacked by autoantibodies frequently produced by patients with connective tissue diseases. Recombinant human SNRPC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

U1 small nuclear ribonucleoprotein C, u1C, Yhc1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

19.8 kDa (182aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

SNRPC, u1 small nuclear ribonucleoprotein C, u1C, Yhc1, ATGP1323-10 µg, ATGP1323-20 µg, ATGP1323-50 µg, ATGP1323-100 µg, ATGP1323-250 µg, ATGP1323-500 µg, ATGP1323-1 mg, ATGP1323-10, ATGP1323-20, ATGP1323-50, ATGP1323-100, ATGP1323-250, ATGP1323-500, ATGP1323-1

Sillekens P.T.G., et al. (1988) Nucleic Acids Res. 16:8307-8321; ; Muto Y., et al. (2004) J. Mol. Biol. 341:185-198

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.3M NaCl, 5mM DTT, 2mM EDTA

Epigenomics (Transcription & Translation)

NP_003084.1

P09234

Human

MPKFYCD YCDTYLTHDS PSVRKTHCSG RKHKENVKDY YQKWMEEQAQ SLIDKTTAAF QQGKIPPTPF SAPPPAGAMI PPPPSLPGPP RPGMMPAPHM GGPPMMPMMG PPPPGMMPVG PAPGMRPPMG GHMPMMPGPP MMRPPARPMM VPTRPGMTRP DR