Recombinant humaan SNRPG-eiwit

Small nuclear ribonucleoprotein polypeptide G, also known as SNRPG, belongs to the snRNP Sm proteins family. There are at least seven isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins plays an essential role in the biogenesis of the snRNPs. The genes encoding human Sm G map to chromosomes 2. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE) . One class of these autoantibodies reacts specifically with native Sm E-F-G complexes. Recombinant human SNRPG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Small nuclear ribonucleoprotein polypeptide G, Sm-G, SMG

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

10.6 kDa (96aa) confirmed by MALDI-TOF

SNRPG, Small nuclear ribonucleoprotein polypeptide G, Sm-G, SMG, ATGP1011-10 µg, ATGP1011-20 µg, ATGP1011-50 µg, ATGP1011-100 µg, ATGP1011-250 µg, ATGP1011-500 µg, ATGP1011-1 mg, ATGP1011-10, ATGP1011-20, ATGP1011-50, ATGP1011-100, ATGP1011-250, ATGP1011-500, ATGP1011-1

Hermann H., et al. (1995) EMBO J. 14 (9) :2076-88.; ; Heinrichs V., et al. (1992) J Mol Biol. 227 (1) :15-28.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 50% glycerol, 0.1M NaCl

Epigenomics (Transcription & Translation)

NP_003087

P62308

Human

MGSSHHHHHH SSGLVPRGSH MSKAHPPELK KFMDKKLSLK LNGGRHVQGI LRGFDPFMNLVIDECVEMAT SGQQNNIGMV VIRGNSIIML EALERV