Recombinant humaan SNTA1-eiwit

SNTA1 is a member of the syntrophin gene family, which is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. Recombinant human SNTA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Syntrophin alpha 1, Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

56.3 kDa (528aa) confirmed by MALDI-TOF

SNTA1, Syntrophin alpha 1, Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1, ATGP1362-10 µg, ATGP1362-20 µg, ATGP1362-50 µg, ATGP1362-100 µg, ATGP1362-250 µg, ATGP1362-500 µg, ATGP1362-1 mg, ATGP1362-10, ATGP1362-20, ATGP1362-50, ATGP1362-100, ATGP1362-250, ATGP1362-500, ATGP1362-1

Newey SE., et al. (2000) Curr Biol. 10 (20) :1295-8.; ; Adams ME., et al. (2000) J Cell Biol. 150 (6) :1385-98.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.

Cytoskeleton

NP_003089.1

Q13424

Human

MASGRRA PRTGLLELRA GAGSGAGGER WQRVLLSLAE DVLTVSPADG DPGPEPGAPR EQEPAQLNGA AEPGAGPPQL PEALLLQRRR VTVRKADAGG LGISIKGGRE NKMPILISKI FKGLAADQTE ALFVGDAILS VNGEDLSSAT HDEAVQVLKK TGKEVVLEVK YMKDVSPYFK NSTGGTSVGW DSPPASPLQR QPSSPGPTPR NFSEAKHMSL KMAYVSKRCT PNDPEPRYLE ICSADGQDTL FLRAKDEASA RSWATAIQAQ VNTLTPRVKD ELQALLAATS TAGSQDIKQI GWLTEQLPSG GTAPTLALLT EKELLLYLSL PETREALSRP ARTAPLIATR LVHSGPSKGS VPYDAELSFA LRTGTRHGVD THLFSVESPQ ELAAWTRQLV DGCHRAAEGV QEVSTACTWN GRPCSLSVHI DKGFTLWAAE PGAARAVLLR QPFEKLQMSS DDGASLLFLD FGGAEGEIQL DLHSCPKTIV FIIHSFLSAK VTRLGLLA