Recombinant humaan SORBS3-eiwit

SORBS3 is an SH3 domain-containing adaptor protein. The presence of SH3 domains play a role in this protein's ability to bind other cytoplasmic molecules and contribute to cystoskeletal organization, cell adhesion and migration, signaling, and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human SORBS3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Vinexin, SCAM-1, SCAM1, SH3D4

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.1 kDa (352aa) confirmed by MALDI-TOF

SORBS3, Vinexin, SCAM-1, SCAM1, SH3D4, ATGP2504-10 µg, ATGP2504-20 µg, ATGP2504-50 µg, ATGP2504-100 µg, ATGP2504-250 µg, ATGP2504-500 µg, ATGP2504-1 mg, ATGP2504-10, ATGP2504-20, ATGP2504-50, ATGP2504-100, ATGP2504-250, ATGP2504-500, ATGP2504-1

Kioka N. et al. (1999) J Cell Biol. 144:59-69; ; Akamatsu M. et al. (1999) J Biol Chem. 274:35933-35937.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Signal Transduction

NP_001018003

O60504

Human

MADGGSP FLGRRDFVYP SSTRDPSASN GGGSPARREE KKRKAARLKF DFQAQSPKEL TLQKGDIVYI HKEVDKNWLE GEHHGRLGIF PANYVEVLPA DEIPKPIKPP TYQVLEYGEA VAQYTFKGDL EVELSFRKGE HICLIRKVNE NWYEGRITGT GRQGIFPASY VQVSREPRLR LCDDGPQLPT SPRLTAAARS ARHPSSPSAL RSPADPIDLG GQTSPRRTGF SFPTQEPRPQ TQNLGTPGPA LSHSRGPSHP LDLGTSSPNT SQIHWTPYRA MYQYRPQNED ELELREGDRV DVMQQCDDGW FVGVSRRTQK FGTFPGNYVA PV