Recombinant humaan SP-D eiwit

SFTPD, as known as Surfactant pulmonary-associated protein D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. It is humoral molecules of the innate immune system, and is considered a functional candidate in chronic periodontitis. Besides it is involved in the development of acute and chronic inflammation of the lung. Several human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. Recombinant human SFTPD protein, fused to His-tag at N-terminus, was expressed in E. coli

Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

18.9 kDa (175aa)

SP-D, Pulmonary surfactant-associated protein D precursor, COLEC7, PSP-D, SFTP4, SP-D, ATGP2731-10 µg, ATGP2731-20 µg, ATGP2731-50 µg, ATGP2731-100 µg, ATGP2731-250 µg, ATGP2731-500 µg, ATGP2731-1 mg, ATGP2731-10, ATGP2731-20, ATGP2731-50, ATGP2731-100, ATGP2731-250, ATGP2731-500, ATGP2731-1

Leth-Larsen R. et al. (2005) J Immunol. 174 : 1532-1538.; ; Hartl D. et al. (2006) Eur J Clin Invest. 36:423-435.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Immunology

NP_003010.4

P35247

Human

VASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF