Recombinant humaan SP-D eiwit

SFTPD, also known as pulmonary surfactant-associated protein D, is a member of the collectin family of innate immune modulators. It contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. This protein interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. Recombinant human SFTPD protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Pulmonary surfactant-associated protein D, SFTPD, COLEC7, PSP-D, SFTP4, SP-D

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

36.5 kDa (363aa)

SP-D, Pulmonary surfactant-associated protein D, SFTPD, COLEC7, PSP-D, SFTP4, SP-D, ATGP3747-10 µg, ATGP3747-20 µg, ATGP3747-50 µg, ATGP3747-100 µg, ATGP3747-250 µg, ATGP3747-500 µg, ATGP3747-1 mg, ATGP3747-10, ATGP3747-20, ATGP3747-50, ATGP3747-100, ATGP3747-250, ATGP3747-500, ATGP3747-1

Soto-Cardenas MJ., et al, (2015) J Rheumatol. 42:111-118.; ; Sorensen GL., et al, (2016) Atherosclerosis. 246:7-12.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Ubiquitination

NP_003010

P35247

Human

Ala

EMKTYSH RTMPSACTLV MCSSVESGLP GRDGRDGREG PRGEKGDPGL PGAAGQAGMP GQAGPVGPKG DNGSVGEPGP KGDTGPSGPP GPPGVPGPAG REGPLGKQGN IGPQGKPGPK GEAGPKGEVG APGMQGSAGA RGLAGPKGER GVPGERGVPG NTGAAGSAGA MGPQGSPGAR GPPGLKGDKG IPGDKGAKGE SGLPDVASLR QQVEALQGQV QHLQAAFSQY KKVELFPNGQ SVGEKIFKTA GFVKPFTEAQ LLCTQAGGQL ASPRSAAENA ALQQLVVAKN EAAFLSMTDS KTEGKFTYPT GESLVYSNWA PGEPNDDGGS EDCVEIFTNG KWNDRACGEK RLVVCEF