Recombinant humaan SPRY4-eiwit

SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS. Recombinant human SPRY4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Protein sprouty homolog 4 isoform 2, Protein sprouty homolog 4 isoform 2, Sprouty homolog 4 (Drosophila)

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

34.9 kDa (322aa)

SPRY4, Protein sprouty homolog 4 isoform 2, Protein sprouty homolog 4 isoform 2, Sprouty homolog 4 (Drosophila), ATGP2326-10 µg, ATGP2326-20 µg, ATGP2326-50 µg, ATGP2326-100 µg, ATGP2326-250 µg, ATGP2326-500 µg, ATGP2326-1 mg, ATGP2326-10, ATGP2326-20, ATGP2326-50, ATGP2326-100, ATGP2326-250, ATGP2326-500, ATGP2326-1

Katoh Y, Katoh M. (2006) . Int J Mol Med 17 (3) : 529-32

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Signal Transduction

NP_001120968

Q9C004

Human

MGSSHHHHHH SSGLVPRGSH MGSMEPPIPQ SAPLTPNSVM VQPLLDSRMS HSRLQHPLTI LPIDQVKTSH VENDYIDNPS LALTTGPKRT RGGAPELAPT PARCDQDVTH HWISFSGRPS SVSSSSSTSS DQRLLDHMAP PPVADQASPR AVRIQPKVVH CQPLDLKGPA VPPELDKHFL LCEACGKCKC KECASPRTLP SCWVCNQECL CSAQTLVNYG TCMCLVQGIF YHCTNEDDEG SCADHPCSCS RSNCCARWSF MGALSVVLPC LLCYLPATGC VKLAQRGYDR LRRPGCRCKH TNSVICKAAS GDAKTSRPDK PF