Recombinant humaan SRA1-eiwit

Steroid receptor RNA activator 1, also known as SRA1, exists as both a RNA transcript and as stably expressed proteins. Also this protein mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2) . SRA1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. It may play a role in tumorigenesis. Recombinant human SRA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Steroid receptor RNA activator 1, pp7684, SRA, SRAP, STRAA1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

18.7 kDa (170aa) confirmed by MALDI-TOF

SRA1, Steroid receptor RNA activator 1, pp7684, SRA, SRAP, STRAA1, ATGP1796-10 µg, ATGP1796-20 µg, ATGP1796-50 µg, ATGP1796-100 µg, ATGP1796-250 µg, ATGP1796-500 µg, ATGP1796-1 mg, ATGP1796-10, ATGP1796-20, ATGP1796-50, ATGP1796-100, ATGP1796-250, ATGP1796-500, ATGP1796-1

Lanz R B., et al. (1999) Cell. 97:17-27; ; Watanabe M., et al. (2001) EMBO J. 20: 1341-1352.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT

Cancer

NP_001030312.2

Q9HD15

Human

VGSGPAS GVEPTSFPVE SEAVMEDVLR PLEQALEDCR GHTRKQVCDD ISRRLALLQE QWAGGKLSIP VKKRMALLVQ ELSSHRWDAA DDIHRSLMVD HVTEVSQWMV GVKRLIAEKR SLFSEEAANE EKSAATAEKN HTIPGFQQAS