Recombinant humaan SSX2-eiwit

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. Recombinant human SSX2, fused to His-tag at N-terminus, was expressed in E. coli.

Synovial sarcoma X breakpoint 2B, Synovial sarcoma, X breakpoint 2B, Cancer/testis antigen family 5, member 2b, CT5.2b

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

24.0 kDa (210aa)

SSX2, Synovial sarcoma X breakpoint 2B, Synovial sarcoma, X breakpoint 2B, Cancer/testis antigen family 5, member 2b, CT5.2b, ATGP2727-10 µg, ATGP2727-20 µg, ATGP2727-50 µg, ATGP2727-100 µg, ATGP2727-250 µg, ATGP2727-500 µg, ATGP2727-1 mg, ATGP2727-10, ATGP2727-20, ATGP2727-50, ATGP2727-100, ATGP2727-250, ATGP2727-500, ATGP2727-1

Neumann F, et al. (2013) Cancer Immunol Immunother, PMID 23619976.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Epigenomics (Transcription & Translation)

NP_001157889

Q16385

Human

MNGDDAFA RRPTVGAQIP EKIQKAFDDI AKYFSKEEWE KMKASEKIFY VYMKRKYEAM TKLGFKATLP PFMCNKRAED FQGNDLDNDP NRGNQVERPQ MTFGRLQGIS PKIMPKKPAE EGNDSEEVPE ASGPQNDGKE LCPPGKPTTS EKIHERSGPK RGEHAWTHRL RERKQLVIYE EISDPEEDDE