Recombinant humaan STAMP2/STEAP4-eiwit

STEAP4 belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+), using NAD (+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human STEAP4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Tumor necrosis factor alpha-induced protein 9, Tumor necrosis factor, Alpha-induced protein 9, DKFZp666D049, FLJ23153, STAMP2, TIARP, TNFAIP9, STEAP4 metalloreductase

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

20.6 kDa (188aa)

Alpha induced protein 9, Alpha-induced protein 9, DKFZp666D049, FLJ23153, STAMP 2, STAMP2, STAMP-2, STEAP4 metalloreductase, TIARP, TNFAIP 9, TNFAIP9, TNFAIP-9, Tumor necrosis factor, Tumor necrosis factor alpha induced protein 9, Tumor necrosis factor alpha-induced protein 9, ATGP2593-10 µg, ATGP2593-20 µg, ATGP2593-50 µg, ATGP2593-100 µg, ATGP2593-250 µg, ATGP2593-500 µg, ATGP2593-1 mg, ATGP2593-010, ATGP2593-020, ATGP2593-050, ATGP2593-100, ATGP2593-250, ATGP2593-500, ATGP2593-01M

Kim, H.Y, et al. (2012) Exp. Mol. Med. 44 (10), 622-632; ; Tanaka, Y., et al. (2012) Clin. Exp. Rheumatol. 30 (1), 99-102;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol

Cancer

NP_078912

Q687X5

Human

MEKT CIDALPLTMN SSEKQETVCI FGTGDFGRSL GLKMLQCGYS VVFGSRNPQK TTLLPSGAEV LSYSEAAKKS GIIIIAIHRE HYDFLTELTE VLNGKILVDI SNNLKINQYP ESNAEYLAHL VPGAHVVKAF NTISAWALQS GALDASRQ