Recombinant humaan Staniocalcine 2/STC-2 eiwit

STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Expression of this gene is induced by estrogen and altered in some breast cancers. Recombinant human STC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Stanniocalcin-2, STC-2, STCRP

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

33 kDa (301aa) confirmed by MALDI-TOF

Stanniocalcin2, STC2, Stanniocalcin-2, STC-2, STCRP, ATGP2142-10 µg, ATGP2142-20 µg, ATGP2142-50 µg, ATGP2142-100 µg, ATGP2142-250 µg, ATGP2142-500 µg, ATGP2142-1 mg, ATGP2142-10, ATGP2142-20, ATGP2142-50, ATGP2142-100, ATGP2142-250, ATGP2142-500, ATGP2142-1

Esseghir S, Kennedy A, et al. (2007) . Clin Cancer Res. 13 (11) :3164-73.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.25M NaCl, 30% glycerol, 1mM DTT

Stem cell

NP_003705

O76061

Human

TDATNPP EGPQDRSSQQ KGRLSLQNTA EIQHCLVNAG DVGCGVFECF ENNSCEIRGL HGICMTFLHN AGKFDAQGKS FIKDALKCKA HALRHRFGCI SRKCPAIREM VSQLQRECYL KHDLCAAAQE NTRVIVEMIH FKDLLLHEPY VDLVNLLLTC GEEVKEAITH SVQVQCEQNW GSLCSILSFC TSAIQKPPTA PPERQPQVDR TKLSRAHHGE AGHHLPEPSS RETGRGAKGE RGSKSHPNAH ARGRVGGLGA QGPSGSSEWE DEQSEYSDIR R