Recombinant humaan STAT1-eiwit

STAT1, also known as STAT91, is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 is activated by peptide hormones, growth factors and cytokines, particularly cytokines of the interferon family. Recombinant human STAT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Signal transducer and activator of transcription 1 91kDa, ISGF-3, STAT91, Transcription factor ISGF-3 components p91/p84, Signal transducer and activator of transcription 1, 91kDa

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

85.2 kDa (732aa) confirmed by MALDI-TOF

STAT1, Signal transducer and activator of transcription 1 91kDa, ISGF-3, STAT91, Transcription factor ISGF-3 components p91/p84, Signal transducer and activator of transcription 1, 91kDa, ATGP0685-10 µg, ATGP0685-20 µg, ATGP0685-50 µg, ATGP0685-100 µg, ATGP0685-250 µg, ATGP0685-500 µg, ATGP0685-1 mg, ATGP0685-10, ATGP0685-20, ATGP0685-50, ATGP0685-100, ATGP0685-250, ATGP0685-500, ATGP0685-1

Farlik M., et al. (2010) Immunity. 33 (1) :25-34.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol

Cancer

NP_644671.1

P42224

Human

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