Recombinant humaan stollingsfactor II/trombine-eiwit

Coagulation factor II, also known as F2, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Recombinant human F2 protein was expressed in E. coli.

Coagulation factor II, Factor II (thrombin), PT

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

33.9 kDa (296aa)

Coagulation Factor II, Thrombin, Coagulation factor II, Factor II (thrombin), PT, ATGP2663-10 µg, ATGP2663-20 µg, ATGP2663-50 µg, ATGP2663-100 µg, ATGP2663-250 µg, ATGP2663-500 µg, ATGP2663-1 mg, ATGP2663-10, ATGP2663-20, ATGP2663-50, ATGP2663-100, ATGP2663-250, ATGP2663-500, ATGP2663-1

Royle NJ, Irwin DM, Koschinsky ML., et al. (1987) Somat. Cell Mol. Genet. 13 (3) : 285-92

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Apoptosis

NP_000497

P00734

Human

MTFGSGEADC GLRPLFEKKS LEDKTERELL ESYIDGRIVE GSDAEIGMSP WQVMLFRKSP QELLCGASLI SDRWVLTAAH CLLYPPWDKN FTENDLLVRI GKHSRTRYER NIEKISMLEK IYIHPRYNWR ENLDRDIALM KLKKPVAFSD YIHPVCLPDR ETAASLLQAG YKGRVTGWGN LKETWTANVG KGQPSVLQVV NLPIVERPVC KDSTRIRITD NMFCAGYKPD EGKRGDACEG DSGGPFVMKS PFNNRWYQMG IVSWGEGCDR DGKYGFYTHV FRLKKWIQKV IDQFGE