Recombinant humaan STRADA-eiwit

STE20-related kinase adapter protein alpha isoform 5, also known as STRADA, is a member of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRADA-LKB1 interaction results in phosphorylation of STRADA and enhanced autophosphorylation of LKB1. Recombinant human STRADA protein, fused to His-tag at N-terminus, was expressed in E. coli.

STE20-related kinase adapter protein alpha isoform 5, LYK5, NY-BR-96, PMSE, Stlk, STRAD

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

37 kDa (337aa)

STRADA, STE20-related kinase adapter protein alpha isoform 5, LYK5, NY-BR-96, PMSE, Stlk, STRAD, ATGP2722-10 µg, ATGP2722-20 µg, ATGP2722-50 µg, ATGP2722-100 µg, ATGP2722-250 µg, ATGP2722-500 µg, ATGP2722-1 mg, ATGP2722-10, ATGP2722-20, ATGP2722-50, ATGP2722-100, ATGP2722-250, ATGP2722-500, ATGP2722-1

Avizienyte E., et al. (1998) Cancer Res. 58: 2087-2090.; ; Baas A F., et al. (2003) EMBO J. 22: 3062-3072.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cell Cycle

NP_001159441

Q7RTN6

Human

MGSSHHHHHH SSGLVPRGSH MGSMSFLVSK PERIRTNDAS SESIASFSKQ EVMSSFLPEG GCYELLTVIG KGFEDLMTVN LARYKPTGEY VTVRRINLEA CSNEMVTFLQ GELHVSKLFN HPNIVPYRAT FIADNELWVV TSFMAYGSAK DLICTHFMDG MNELAIAYIL QGVLKALDYI HHMGYVHRSV KASHILISVD GKVYLSGLRS NLSMISHGQR QRVVHDFPKY SVKVLPWLSP EVLQQNLQGY DAKSDIYSVG ITACELANGH VPFKDMPATQ MLLEKLNGTV PCLLDTSTIP AEELTMSPSR SVANSGLSDS LTTSTPRPSN GPVPAPS