Recombinant humaan supplementfactor D-eiwit

CFD, also known as adipsin, is involved in the alternative complement pathway of the complement system where it cleaves factor B. This protein is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, it has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. Recombinant human CFD protein, fused to His-tag at N-terminus, was expressed in E. coli.

Complement factor D, DF, AND, PFD, ADIPSIN

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

26.6 kDa (249aa)

Complement Factor D, Complement factor D, DF, AND, PFD, ADIPSIN, ATGP1877-10 µg, ATGP1877-20 µg, ATGP1877-50 µg, ATGP1877-100 µg, ATGP1877-250 µg, ATGP1877-500 µg, ATGP1877-1 mg, ATGP1877-10, ATGP1877-20, ATGP1877-50, ATGP1877-100, ATGP1877-250, ATGP1877-500, ATGP1877-1

Narayana SV. et al. (1994) J Mol Biol. 235:695-708.; ; Ronti T. et al. (2006) Clin Endocrinol (Oxf) . 64:355-365.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Immunology

NP_001919

P00746

Human

MGSSHHHHHH SSGLVPRGSH MILGGREAEA HARPYMASVQ LNGAHLCGGV LVAEQWVLSA AHCLEDAADG KVQVLLGAHS LSQPEPSKRL YDVLRAVPHP DSQPDTIDHD LLLLQLSEKA TLGPAVRPLP WQRVDRDVAP GTLCDVAGWG IVNHAGRRPD SLQHVLLPVL DRATCNRRTH HDGAITERLM CAESNRRDSC KGDSGGPLVC GGVLEGVVTS GSRVCGNRKK PGIYTRVASY AAWIDSVLA