Recombinant humaan SVH/ARMC10-eiwit

AMRC10 is a protein that contains an armadillorepeat and transmembrane domain. The protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. upregulation of this gene may play a role in hepatocellular carcinoma. Recombinant human AMRC10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Armadillo repeat-containing protein 10 isoform b, PNAS-112, PNAS112, PSEC0198, SVH

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

33.6 kDa (304aa) confirmed by MALDI-TOF

ARMC10, Armadillo repeat-containing protein 10 isoform b, PNAS-112, PNAS112, PSEC0198, SVH, ATGP2084-10 µg, ATGP2084-20 µg, ATGP2084-50 µg, ATGP2084-100 µg, ATGP2084-250 µg, ATGP2084-500 µg, ATGP2084-1 mg, ATGP2084-10, ATGP2084-20, ATGP2084-50, ATGP2084-100, ATGP2084-250, ATGP2084-500, ATGP2084-1

Zhou, X., et al. (2007) FEBS Lett. 581 (25), 4943-4948; ; Huang, R., et al. (2003) Cancer Res. 63 (13), 3775-3782

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Cancer

NP_001154481

Q8N2F6

Human

TRGRRRG DRELGIRSSK SAEDLTDGSY DDVLNAEQLQ KLLYLLESTE DPVIIERALI TLGNNAAFSV NQAIIRELGG IPIVANKINH SNQSIKEKAL NALNNLSVNV ENQIKIKIYI SQVCEDVFSG PLNSAVQLAG LTLLTNMTVT NDHQHMLHSY ITDLFQVLLT GNGNTKVQVL KLLLNLSENP AMTEGLLRAQ VDSSFLSLYD SHVAKEILLR VLTLFQNIKN CLKIEGHLAV QPTFTEGSLF FLLHGEECAQ KIRALVDHHD AEVKEKVVTI IPKI