Recombinant humaan Syndecaan-2/SDC2-eiwit

SDC2, also known as syndecan 2, is a conserved family of heparan- and chondroitin-sulfate carrying transmembrane protein. It is a cell membrane proteoglycans that can modulate the activity and dynamics of some growth factor receptors and integrins. It is expressed in hepatic stellate cells (HSCs), a key cell type involved in matrix deposition in liver fibrotic disorders. It has been implicated in the formation of specialized membrane domains and functions as a direct link between the extracellular environment and the organization of the cortical cytoplasm. Recombinant human SDC2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Syndecan 2, SDC2, CD362, HSPG, HSPG1, SYND2, Syndecan proteoglycan 2, Fibroglycan, Heparan sulfate proteoglycan core protein

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

15 kDa (135aa)

SDC2, Syndecan 2, SDC2, CD362, HSPG, HSPG1, SYND2, ATGP3625-10 µg, ATGP3625-20 µg, ATGP3625-50 µg, ATGP3625-100 µg, ATGP3625-250 µg, ATGP3625-500 µg, ATGP3625-1 mg, ATGP3625-10, ATGP3625-20, ATGP3625-50, ATGP3625-100, ATGP3625-250, ATGP3625-500, ATGP3625-1

Renga B., et al. (2014) PLoS One. 9:e94798.; ; Essner JJ., et al. (2006) Int J Biochem Cell Biol. 38:152-156.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_002989

P34741

Human

Ala

ADPESRAELT SDKDMYLDNS SIEEASGVYP IDDDDYASAS GSGADEDVES PELTTSRPLP KILLTSAAPK VETTTLNIQN KIPAQTKSPE ETDKEKVHLS DSERKMDPAE EDTNVYTEKH SDSLFKRTEH HHHHH