Recombinant humaan Syntaxine 12 eiwit

Syntaxin 12, also known as, belongs to the syntaxin family. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. STX12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I) . Recombinant human STX12 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Syntaxin 12, STX13, STX14

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

31.0 kDa (272aa) confirmed by MALDI-TOF

Syntaxin12, Syntaxin 12, STX13, STX14, ATGP1536-10 µg, ATGP1536-20 µg, ATGP1536-50 µg, ATGP1536-100 µg, ATGP1536-250 µg, ATGP1536-500 µg, ATGP1536-1 mg, ATGP1536-10, ATGP1536-20, ATGP1536-50, ATGP1536-100, ATGP1536-250, ATGP1536-500, ATGP1536-1

Tang B L., et al. (1998) J Biol Chem. 273:6944-6950.; ; Prekeris R., et al. (1998) J Cell Biol. 143: 957-971.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,1mM DTT

Transportation

NP_803173.1

Q86Y82

Human

MSYGPL DMYRNPGPSG PQLRDFSSII QTCSGNIQRI SQATAQIKNL MSQLGTKQDS SKLQENLQQL QHSTNQLAKE TNELLKELGS LPLPLSTSEQ RQQRLQKERL MNDFSAALNN FQAVQRRVSE KEKESIARAR AGSRLSAEER QREEQLVSFD SHEEWNQMQS QEDEVAITEQ DLELIKERET AIRQLEADIL DVNQIFKDLA MMIHDQGDLI DSIEANVESS EVHVERATEQ LQRAAYYQKK SR