Recombinant humaan Syntaxine 4 eiwit

Syntaxin 4, also known as STX4, belongs to thesyntaxin/epimorphin family of proteins. Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. Syntaxin 4 is crucial for normal insulin-stimulated glucose uptake in skeletal muscle and decreases in Syntaxin 4 protein levels result in reduction of whole-body insulin-stimulated glucose metabolism. Recombinant human STX4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Syntaxin 4, p35-2, STX4A

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

34.7 kDa (300aa) confirmed by MALDI-TOF

Syntaxin4, Syntaxin 4, p35-2, STX4A, ATGP1667-10 µg, ATGP1667-20 µg, ATGP1667-50 µg, ATGP1667-100 µg, ATGP1667-250 µg, ATGP1667-500 µg, ATGP1667-1 mg, ATGP1667-10, ATGP1667-20, ATGP1667-50, ATGP1667-100, ATGP1667-250, ATGP1667-500, ATGP1667-1

Yang C., et al. (2001) J Clin Invest. 107: 1311-1318; ; Bennett M K., et al. (1993) Cell. 74: 863-873.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol,1mM DTT

Signal Transduction

NP_004595

Q12846

Human

MGSSHHHHHH SSGLVPRGSH MGSHMMRDRT HELRQGDDSS DEEDKERVAL VVHPGTARLG SPDEEFFHKV RTIRQTIVKL GNKVQELEKQ QVTILATPLP EESMKQELQN LRDEIKQLGR EIRLQLKAIE PQKEEADENY NSVNTRMRKT QHGVLSQQFV ELINKCNSMQ SEYREKNVER IRRQLKITNA GMVSDEELEQ MLDSGQSEVF VSNILKDTQV TRQALNEISA RHSEIQQLER SIRELHDIFT FLATEVEMQG EMINRIEKNI LSSADYVERG QEHVKTALEN QKKARKKKVL