Recombinant humaan Syntenine-2/SDCBP2-eiwit

SDCBP2 contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Recombinant human SDCBP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Syndecan binding protein, SITAC, SITAC18, ST-2, Syntenin-2, Similar to TACIP18

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

34.0 kDa (315aa) confirmed by MALDI-TOF

SDCBP2, Syndecan binding protein, SITAC, SITAC18, ST-2, ATGP1824-10 µg, ATGP1824-20 µg, ATGP1824-50 µg, ATGP1824-100 µg, ATGP1824-250 µg, ATGP1824-500 µg, ATGP1824-1 mg, ATGP1824-10, ATGP1824-20, ATGP1824-50, ATGP1824-100, ATGP1824-250, ATGP1824-500, ATGP1824-1

Zimmermann, P. (2006) Biochim. Biophys. Acta 1761 (8), 947-956; ; Koroll, M., (2001) J. Biol. Chem. 276 (14), 10646-10654;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Signal Transduction

NP_001186713

Q9H190

Human

MSSLYPS LEDLKVDQAI QAQVRASPKM PALPVQATAI SPPPVLYPNL AELENYMGLS LSSQEVQESL LQIPEGDSTA VSGPGPGQMV APVTGYSLGV RRAEIKPGVR EIHLCKDERG KTGLRLRKVD QGLFVQLVQA NTPASLVGLR FGDQLLQIDG RDCAGWSSHK AHQVVKKASG DKIVVVVRDR PFQRTVTMHK DSMGHVGFVI KKGKIVSLVK GSSAARNGLL TNHYVCEVDG QNVIGLKDKK IMEILATAGN VVTLTIIPSV IYEHMVKKLP PVLLHHTMDH SIPDA