Recombinant humaan TACI/TNFRSF13B-eiwit

TNFRSF13B, also known as TACI, is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML) . It was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family. It controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis. Recombinant human TNFRSF13B protein, fused to His-tag at N-terminus, was expressed in E. coli.

TNF receptor superfamily member 13B, Transmembrane activator and CAML interactor, TACI, CD267, IGAD2

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

20.9 kDa (188aa)

CD 267, CD267, CD267 antigen, CVID, CVID2, FLJ39942, IGAD2, MGC133214, MGC39952, OTTHUMP00000065442, RYZN, TACI, TNF receptor superfamily member 13B, TNFRSF 13B, TNFRSF13B, TNFRSF13B protein, TR13B_HUMAN, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor 13B, Tumor necrosis factor receptor superfamily member 13B, ATGP1989-10 µg, ATGP1989-20 µg, ATGP1989-50 µg, ATGP1989-100 µg, ATGP1989-250 µg, ATGP1989-500 µg, ATGP1989-1 mg, ATGP1989-010, ATGP1989-020, ATGP1989-050, ATGP1989-100, ATGP1989-250, ATGP1989-500, ATGP1989-01M

Wu Y. et al. (2000) J Biol Chem. 275:35478-35485.; ; von Bulow Gu. et al. (1997) Science. 278:138-141.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Immunology

NP_036584

O14836

Human

MGSSHHHHHH SSGLVPRGSH MGSMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYS