Recombinant humaan TADA3-eiwit

Transcriptional adapter 3 isoform a, also known as TATD3, is a subunit of 2 histone acetyltransferase complexes. TATD3 is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. Recombinant human TATD3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Transcriptional adapter 3 isoform a, Transcriptional adapter 3 isoform a, ADA3, hADA3, NGG1, TADA3L

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

51.3 kDa (455aa)

TADA3, Transcriptional adapter 3 isoform a, Transcriptional adapter 3 isoform a, ADA3, hADA3, NGG1, TADA3L, ATGP2312-10 µg, ATGP2312-20 µg, ATGP2312-50 µg, ATGP2312-100 µg, ATGP2312-250 µg, ATGP2312-500 µg, ATGP2312-1 mg, ATGP2312-10, ATGP2312-20, ATGP2312-50, ATGP2312-100, ATGP2312-250, ATGP2312-500, ATGP2312-1

Li CW., et al. (2010) Nucleic Acids Res. 38 (16) :5291-303.; ; Hu Y., et al. (2009) Cancer Invest. 27 (3) :298-306.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Epigenomics (Transcription & Translation)

NP_006345

O75528

Human

MGSSHHHHHH SSGLVPRGSH MGSMSELKDC PLQFHDFKSV DHLKVCPRYT AVLARSEDDG IGIEELDTLQ LELETLLSSA SRRLRVLEAE TQILTDWQDK KGDRRFLKLG RDHELGAPPK HGKPKKQKLE GKAGHGPGPG PGRPKSKNLQ PKIQEYEFTD DPIDVPRIPK NDAPNRFWAS VEPYCADITS EEVRTLEELL KPPEDEAEHY KIPPLGKHYS QRWAQEDLLE EQKDGARAAA VADKKKGLMG PLTELDTKDV DALLKKSEAQ HEQPEDGCPF GALTQRLLQA LVEENIISPM EDSPIPDMSG KESGADGAST SPRNQNKPFS VPHTKSLESR IKEELIAQGL LESEDRPAED SEDEVLAELR KRQAELKALS AHNRTKKHDL LRLAKEEVSR QELRQRVRMA DNEVMDAFRK IMAARQKKRT PTKKEKDQAW KTLKERESIL KLLDG