Recombinant humaan TAF15-eiwit

TAF15 is a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human TAF15 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

TATA-binding protein-associated factor 2N isoform 1, TATA-binding protein-associated factor 2N isoform 1, Npl3, RBP56, TAF2N, TAFII68

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

30kDa (282aa) confirmed by MALDI-TOF

TAF15, TATA-binding protein-associated factor 2N isoform 1, TATA-binding protein-associated factor 2N isoform 1, Npl3, RBP56, TAF2N, TAFII68, ATGP2466-10 µg, ATGP2466-20 µg, ATGP2466-50 µg, ATGP2466-100 µg, ATGP2466-250 µg, ATGP2466-500 µg, ATGP2466-1 mg, ATGP2466-10, ATGP2466-20, ATGP2466-50, ATGP2466-100, ATGP2466-250, ATGP2466-500, ATGP2466-1

Martini A, La Starza R, et al. (2002) . Cancer Res. 62 (19) :5408-12.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Epigenomics (Transcription & Translation)

NP_631961

Q92804

Human

SYHSQRE NYSHHTQDDR RDVSRYGEDN RGYGGSQGGG RGRGGYDKDG RGPMTGSSGG DRGGFKNFGG HRDYGPRTDA DSESDNSDNN TIFVQGLGEG VSTDQVGEFF KQIGIIKTNK KTGKPMINLY TDKDTGKPKG EATVSFDDPP SAKAAIDWFD GKEFHGNIIK VSFATRRPEF MRGGGSGGGR RGRGGYRGRG GFQGRGGDPK SGDWVCPNPS CGNMNFARRN SCNQCNEPRP EDSRPSGGDF RGRGYGGERG YR