Recombinant humaan TALDO1-eiwit

TALDO1 is a key enzyme of the non-oxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This protein transfers a dihydroxyacetone group from donor compounds (fructose 6-phosphate or sedoheptulose 7-phosphate) to aldehyde acceptor compounds. It is expressed at selectively high levels in oligodendrocytes of the brain. Deficiency of TALDO1 causes accumulation of erythritol, D-arabitol, and ribitol. Recombinant human TALDO1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Transaldolase 1, TAL, TAL-H, TALDOR, TALH, TALDO1, Transaldolase 1

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

39.7 kDa (357aa) confirmed by MALDI-TOF

TALDO1, Transaldolase 1, TAL, TAL-H, TALDOR, TALH, TALDO1, Transaldolase 1, ATGP0666-10 µg, ATGP0666-20 µg, ATGP0666-50 µg, ATGP0666-100 µg, ATGP0666-250 µg, ATGP0666-500 µg, ATGP0666-1 mg, ATGP0666-10, ATGP0666-20, ATGP0666-50, ATGP0666-100, ATGP0666-250, ATGP0666-500, ATGP0666-1

Sprenger GA., et al. (2009) Int J Biochem Cell Biol. 41 (7) :1482-94.; ; Saudubray JM., et al (2006) J Pediatr. 149 (5) :713-7.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Cancer

NP_006746

P37837

Human

MGSSHHHHHH SSGLVPRGSH MSSSPVKRQR MESALDQLKQ FTTVVADTGD FHAIDEYKPQ DATTNPSLIL AAAQMPAYQE LVEEAIAYGR KLGGSQEDQI KNAIDKLFVL FGAEILKKIP GRVSTEVDAR LSFDKDAMVA RARRLIELYK EAGISKDRIL IKLSSTWEGI QAGKELEEQH GIHCNMTLLF SFAQAVACAE AGVTLISPFV GRILDWHVAN TDKKSYEPLE DPGVKSVTKI YNYYKKFSYK TIVMGASFRN TGEIKALAGC DFLTISPKLL GELLQDNAKL VPVLSAKAAQ ASDLEKIHLD EKSFRWLHNE DQMAVEKLSD GIRKFAADAV KLERMLTERM FNAENGK