Recombinant humaan TARBP2-eiwit

TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. This protein contains 3 DRBM (double-stranded RNA-binding) domains. It may also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. TARBP2 binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. Recombinant human TARBP2 protein was expressed in E. coli.

TAR RNA binding protein 2 isoform b, LOQS, TRBP, TRBP1, TRBP2

E.coli

Human

Non-Tagged

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

36.9 kDa (345aa)

TARBP2, TAR RNA binding protein 2 isoform b, LOQS, TRBP, TRBP1, TRBP2, ATGP2702-10 µg, ATGP2702-20 µg, ATGP2702-50 µg, ATGP2702-100 µg, ATGP2702-250 µg, ATGP2702-500 µg, ATGP2702-1 mg, ATGP2702-10, ATGP2702-20, ATGP2702-50, ATGP2702-100, ATGP2702-250, ATGP2702-500, ATGP2702-1

Dorin D., et al (2003) . J. Biol. Chem. 278:4440-4448; ; Gregory R.I., et al (2005) . Cell 123:631-640;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Epigenomics (Transcription & Translation)

NP_004169

Q15633

Human

MLAANPGKTP ISLLQEYGTR IGKTPVYDLL KAEGQAHQPN FTFRVTVGDT SCTGQGPSKK AAKHKAAEVA LKHLKGGSML EPALEDSSSF SPLDSSLPED IPVFTAAAAA TPVPSVVLTR SPPMELQPPV SPQQSECNPV GALQELVVQK GWRLPEYTVT QESGPAHRKE FTMTCRVERF IEIGSGTSKK LAKRNAAAKM LLRVHTVPLD ARDGNEVEPD DDHFSIGVGS RLDGLRNRGP GCTWDSLRNS VGEKILSLRS CSLGSLGALG PACCRVLSEL SEEQAFHVSY LDIEELSLSG LCQCLVELST QPATVCHGSA TTREAARGEA ARRALQYLKI MAGSK