Recombinant humaan Tau 381 (1N3R) /MAPT eiwit

Tau, also known as microtubule-associated protein tau (MAPT), is a protein that stabilizes microtubules. It is abundant in neurons in the central nervous system and is less common elsewhere. When this protein is defective, and no longer stabilizes microtubules properly, it can result in dementias, such as Alzheimer's disease. Recombinant human Tau protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Microtubule-associated protein tau isoform 7, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, G protein beta1/gamma2 subunit-interacting factor 1, protein phosphatase 1 regulatory subunit 103, MTBT1, PPND, FTDP-17, TAU, MSTD, MTBT2, FLJ31424, MGC138549, PPP1R103, tau-40, DDPAC, MAPTL

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by BCA assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

41.8 kDa (401aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

TAU, Microtubule-associated protein tau isoform CRA_f, Microtubule-associated protein tau, isoform CRA_f, MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, ATGP0814-10 µg, ATGP0814-20 µg, ATGP0814-50 µg, ATGP0814-100 µg, ATGP0814-250 µg, ATGP0814-500 µg, ATGP0814-1 mg, ATGP0814-10, ATGP0814-20, ATGP0814-50, ATGP0814-100, ATGP0814-250, ATGP0814-500, ATGP0814-1

Cross D., et al. (1993), J Cell Sci. 105: 51-60.; ; Lubke u., et al. (1994), Am. J. Pathol. 145: 175-188

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 0.1mM PMSF

Neuroscience

NP_001190180.1

P10636

Human

MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKESPLQT PTEDGSEEPG SETSDAKSTP TAEAEEAGIG DTPSLEDEAA GHVTQARMVS KSKDGTGSDD KKAKGADGKT KIATPRGAAP PGQKGQANAT RIPAKTPPAP KTPPSSGEPP KSGDRSGYSS PGSPGTPGSR SRTPSLPTPP TREPKKVAVV RTPPKSPSSA KSRLQTAPVP MPDLKNVKSK IGSTENLKHQ PGGGKVQIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L