Recombinant humaan TCEAL7 eiwit

TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines. Recombinant human TCEAL7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Transcription elongation factor A (SII) -like 7, MPMGp800C04260Q003

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

14.8 kDa (124aa) confirmed by MALDI-TOF

TCEAL7, Transcription elongation factor A (SII) -like 7, MPMGp800C04260Q003, ATGP1616-10 µg, ATGP1616-20 µg, ATGP1616-50 µg, ATGP1616-100 µg, ATGP1616-250 µg, ATGP1616-500 µg, ATGP1616-1 mg, ATGP1616-10, ATGP1616-20, ATGP1616-50, ATGP1616-100, ATGP1616-250, ATGP1616-500, ATGP1616-1

Lafferty-Whyte, K., et al. (2010) Neoplasia 12 (5), 405-414; ; Rattan, R., et al. (2010) Oncogene 29 (9), 1362-1373

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl, 2mM DTT

Epigenomics (Transcription & Translation)

NP_689491

Q9BRU2

Human

MGSSHHHHHH SSGLVPRGSH MGSHMQKPCK ENEGKPKCSV PKREEKRPYG EFERQQTEGN FRQRLLQSLE EFKEDIDYRH FKDEEMTREG DEMERCLEEI RGLRKKFRAL HSNHRHSRDR PYPI