Recombinant humaan TCF4-eiwit

TCF4, also known as immunoglobulin transcription factor 2 and transcription factor 4, is a protein acting as a transcription factor. This protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. It is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Recombinant human TCF4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Transcription factor 4, bHLHb19, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

56.6 kDa (530aa)

TCF4, Transcription factor 4, bHLHb19, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, ATGP2605-10 µg, ATGP2605-20 µg, ATGP2605-50 µg, ATGP2605-100 µg, ATGP2605-250 µg, ATGP2605-500 µg, ATGP2605-1 mg, ATGP2605-10, ATGP2605-20, ATGP2605-50, ATGP2605-100, ATGP2605-250, ATGP2605-500, ATGP2605-1

Sepp, M. et al. (2012) Human Molecular Genetics. 21:2873-2888; ; de Pontual L. et al. (2009) Hum. Mutat. 30:669-676.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Stem cell

NP_001230165.1

P15884

Human

MKFKQCR CSDTGLCCLD HEGKAEVYAP SASTADYNRD SPGYPSSKPA TSTFPSSFFM QDGHHSSDPW SSSSGMNQPG YAGMLGNSSH IPQSSSYCSL HPHERLSYPS HSSADINSSL PPMSTFHRSG TNHYSTSSCT PPANGTDSIM ANRGSGAAGS SQTGDALGKA LASIYSPDHT NNSFSSNPST PVGSPPSLSA GTAVWSRNGG QASSSPNYEG PLHSLQSRIE DRLERLDDAI HVLRNHAVGP STAMPGGHGD MHGIIGPSHN GAMGGLGSGY GTGLLSANRH SLMVGTHRED GVALRGSHSL LPNQVPVPQL PVQSATSPDL NPPQDPYRGM PPGLQGQSVS SGSSEIKSDD EGDENLQDTK SSEDKKLDDD KKDIKSITSN NDDEDLTPEQ KAEREKERRM ANNARERLRV RDINEAFKEL GRMVQLHLKS DKPQTKLLIL HQAVAVILSL EQQVRERNLN PKAACLKRRE EEKVSSEPPP LSLAGPHPGM GDASNHMGQM