Recombinant humaan TEN1-eiwit

TEN1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Recombinant human TEN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

CST complex subunit TEN1, TEN1 telomerase capping complex subunit homolog, C17orf106

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

16.2 kDa (146aa) confirmed by MALDI-TOF

TEN1, CST complex subunit TEN1, TEN1 telomerase capping complex subunit homolog, C17orf106, ATGP2166-10 µg, ATGP2166-20 µg, ATGP2166-50 µg, ATGP2166-100 µg, ATGP2166-250 µg, ATGP2166-500 µg, ATGP2166-1 mg, ATGP2166-10, ATGP2166-20, ATGP2166-50, ATGP2166-100, ATGP2166-250, ATGP2166-500, ATGP2166-1

Miyake Y., et al. (2009) Mol. Cell 36:193-206.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Epigenomics (Transcription & Translation)

NP_001106795

Q86WV5

Human

MMLPKPG TYYLPWEVSA GQVPDGSTLR TFGRLCLYDM IQSRVTLMAQ HGSDQHQVLV CTKLVEPFHA QVGSLYIVLG ELQHQQDRGS VVKARVLTCV EGMNLPLLEQ AIREQRLYKQ ERGGSQ