Recombinant humaan TES-eiwit

TES is a tumor suppressor protein and may play role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. This protein localizes to cell-cell contacts and actin stress fibres, and interacts with a variety of cytoskeletal proteins including Zyxin, Mena, VASP, Talin and Actin. The ability of TES to associate with alpha-actinin, paxillin and Zyxin is dependent on the conformational state of the molecule. Recombinant human TES protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Testin, TESS, TESS-2, Testin

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

50.1 kDa (441aa) confirmed by MALDI-TOF

TES, Testin, TESS, TESS-2, Testin, ATGP0684-10 µg, ATGP0684-20 µg, ATGP0684-50 µg, ATGP0684-100 µg, ATGP0684-250 µg, ATGP0684-500 µg, ATGP0684-1 mg, ATGP0684-10, ATGP0684-20, ATGP0684-50, ATGP0684-100, ATGP0684-250, ATGP0684-500, ATGP0684-1

Qiu H., et al. (2010) Cancer Sci. 101 (5) :1255-60.; ; Sato T., et al. (2003) J Biol Chem. 278 (48) :47534-44.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol

Cancer

NP_056456

Q9UGI8

Human

MDLENKVKKM GLGHEQGFGA PCLKCKEKCE GFELHFWRKI CRNCKCGQEE HDVLLSNEED RKVGKLFEDT KYTTLIAKLK SDGIPMYKRN VMILTNPVAA KKNVSINTVT YEWAPPVQNQ ALARQYMQML PKEKQPVAGS EGAQYRKKQL AKQLPAHDQD PSKCHELSPR EVKEMEQFVK KYKSEALGVG DVKLPCEMDA QGPKQMNIPG GDRSTPAAVG AMEDKSAEHK RTQYSCYCCK LSMKEGDPAI YAERAGYDKL WHPACFVCST CHELLVDMIY FWKNEKLYCG RHYCDSEKPR CAGCDELIFS NEYTQAENQN WHLKHFCCFD CDSILAGEIY VMVNDKPVCK PCYVKNHAVV CQGCHNAIDP EVQRVTYNNF SWHASTECFL CSCCSKCLIG QKFMPVEGMV FCSVECKKRM S