Recombinant humaan TFPI-2-eiwit

TFPI2, as known as tissue factor pathway inhibitor 2 isoform 1, is a kunitz-type serine proteinase inhibitor, which is produced and secreted into endothelial cell matrix (ECM) by endothelial cells, smooth muscle cells, fibroblasts, keratinocytes, and urothelium. Also, this protein has been shown to inhibit ECM proteases essential for angiogenesis and metastasis. Recombinant human TFPI2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Tissue factor pathway inhibitor 2 isoform 1, TFPI2, PP5, REF1, TFPI-2

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

22.9 kDa (199aa)

TFPI2, Tissue factor pathway inhibitor 2 isoform 1, TFPI2, PP5, REF1, TFPI-2, ATGP3367-10 µg, ATGP3367-20 µg, ATGP3367-50 µg, ATGP3367-100 µg, ATGP3367-250 µg, ATGP3367-500 µg, ATGP3367-1 mg, ATGP3367-10, ATGP3367-20, ATGP3367-50, ATGP3367-100, ATGP3367-250, ATGP3367-500, ATGP3367-1

Arakawa N., et al. (2013) J. Proteome Res. 12:4340-4350.; ; Papareddy P., et al. (2012) PLoS ONE 7:E52772.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_006519

P48307

Human

Asp23

DAAQEPTGNN AEICLLPLDY GPCRALLLRY YYDRYTQSCR QFLYGGCEGN ANNFYTWEAC DDACWRIEKV PKVCRLQVSV DDQCEGSTEK YFFNLSSMTC EKFFSGGCHR NRIENRFPDE ATCMGFCAPK KIPSFCYSPK DEGLCSANVT RYYFNPRYRT CDAFTYTGCG GNDNNFVSRE DCKRACAKAL KLEHHHHHH