Recombinant humaan TGF-beta 1-eiwit

Transforming growth factor beta 1 (TGF-beta1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. Many cells synthesize TGFb1 and almost all of them have specific receptors for it. It positively and negatively regulates many other growth factors. Also, TGF-beta1 plays an important role in bone remodeling, controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Recombinant TGF-beta1 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Transforming growth factor beta 1, CED, DPD1, TGFB, Transforming growth factor beta 1, TGFB1, TGFbeta, Camurati-Engelmann disease

E.coli

Human

Non-Tagged

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

12.9 kDa (113aa) confirmed by MALDI-TOF

TGF-b1, Transforming growth factor beta 1, CED, DPD1, TGFB, Transforming growth factor beta 1, TGFB1, TGFbeta, Camurati-Engelmann disease, TGFb1, TGF beta, ATGP0383-10 µg, ATGP0383-20 µg, ATGP0383-50 µg, ATGP0383-100 µg, ATGP0383-250 µg, ATGP0383-500 µg, ATGP0383-1 mg, ATGP0383-10, ATGP0383-20, ATGP0383-50, ATGP0383-100, ATGP0383-250, ATGP0383-500, ATGP0383-1

Lebman DA., et al. (1999) Microbes Infect. 1 (15) :1297-304.; ; Wahl SM., et al. (1988) J Immunol. 140 (9) :3026-32. ;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol

Hormones & Cytokines

NP_000651.3

P01137

Human

MALDTNYCFS STEKNCCVRQ LYIDFRKDLG WKWIHEPKGY HANFCLGPCP YIWSLDTQYS KVLALYNQHN PGASAAPCCV PQALEPLPIV YYVGRKPKVE QLSNMIVRSC KCS