Recombinant humaan TGFBRAP1-eiwit

TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. It may recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. Recombinant human TGFBRAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Transforming growth factor beta receptor associated protein 1, Transforming growth factor, beta receptor associated protein 1, TRAP-1, TRAP1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

33 kDa (296aa)

TGFBRAP1, Transforming growth factor beta receptor associated protein 1, Transforming growth factor, beta receptor associated protein 1, TRAP-1, TRAP1, ATGP2588-10 µg, ATGP2588-20 µg, ATGP2588-50 µg, ATGP2588-100 µg, ATGP2588-250 µg, ATGP2588-500 µg, ATGP2588-1 mg, ATGP2588-10, ATGP2588-20, ATGP2588-50, ATGP2588-100, ATGP2588-250, ATGP2588-500, ATGP2588-1

Felts SJ, Owen BA, et al. (2000) . J Biol Chem. 275 (5) :3305-12.; ; Simmons AD, Musy MM, et al. (1999) . Hum Mol Genet. 8 (12) :2155-64.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cancer

NP_004248

Q8WUH2

Human

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT