Recombinant humaan THRSP-eiwit

THRSP is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. Recombinant human THRSP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Thyroid hormone-inducible hepatic protein, Lpgp, LPGP1, S14, SPOT14, THRP

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

18.9 kDa (169aa) confirmed by MALDI-TOF

THRSP, Thyroid hormone-inducible hepatic protein, Lpgp, LPGP1, S14, SPOT14, THRP, ATGP2127-10 µg, ATGP2127-20 µg, ATGP2127-50 µg, ATGP2127-100 µg, ATGP2127-250 µg, ATGP2127-500 µg, ATGP2127-1 mg, ATGP2127-10, ATGP2127-20, ATGP2127-50, ATGP2127-100, ATGP2127-250, ATGP2127-500, ATGP2127-1

Taviaux S, Planells R, et al. (1997) . Cytogenet Cell Genet. 76 (3-4) :219-20.; ; Moncur JT, Park JP, et al. (2003) . Proc Natl Acad Sci u S A. 95 (12) :6989-94.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Metabolism

NP_003242

Q92748

Human

MQVLTKR YPKNCLLTVM DRYAAEVHNM EQVVMIPSLL RDVQLSGPGG QAQAEAPDLY TYFTMLKAIC VDVDHGLLPR EEWQAKVAGS EENGTAETEE VEDESASGEL DLEAQFHLHF SSLHHILMHL TEKAQEVTRK YQEMTGQVW