Recombinant humaan TIAF1-eiwit

TGFB1-induced anti-apoptotic factor 1, also known as TIAF1, inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. This protein involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. Recombinant human TIAF1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

TGFB1-induced anti-apoptotic factor 1, MAJN, SPR210

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

16.6 kDa (152aa)

TIAF1, TGFB1-induced anti-apoptotic factor 1, MAJN, SPR210, ATGP1708-10 µg, ATGP1708-20 µg, ATGP1708-50 µg, ATGP1708-100 µg, ATGP1708-250 µg, ATGP1708-500 µg, ATGP1708-1 mg, ATGP1708-10, ATGP1708-20, ATGP1708-50, ATGP1708-100, ATGP1708-250, ATGP1708-500, ATGP1708-1

Chang N.-S., et al. (1998) Biochem. Biophys. Res. Commun. 253:743-749; ; van der Leij J., et al. (2003) Transplantation. 75:2076-2082

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Signal Transduction

NP_004731

O95411

Human

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSS PSSPFREQSF LCAAGDAGEE SRVQVLKNEV RRGSPVLLGW VEQAYADKCV CGPSAPPAPT PPSLSQRVMC NDLFKVNPFQ LQQFRADPST ASLLLCPGGL DHKLNLRGKA WG