Recombinant humaan TIM-1/KIM-1/HAVCR-eiwit

HAVCR1 also known as Hepatitis A virus cellular receptor 1. The protein is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. Recombinant human HAVCR1, fused to His-tag at N-terminus, was expressed in E. coli.

Hepatitis A virus cellular receptor 1 homolog, Kidney injury molecule 1, KIM-1, T cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T cell membrane protein 1, T-cell immunoglobulin mucin receptor 1, TIM-1, CD365

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

31.9 kDa (298aa)

TIM1, KIM1, HAVCR, Hepatitis A virus cellular receptor 1, Hepatitis A virus cellular receptor 1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1, ATGP3034-10 µg, ATGP3034-20 µg, ATGP3034-50 µg, ATGP3034-100 µg, ATGP3034-250 µg, ATGP3034-500 µg, ATGP3034-1 mg, ATGP3034-10, ATGP3034-20, ATGP3034-50, ATGP3034-100, ATGP3034-250, ATGP3034-500, ATGP3034-1

Wojcik G., et al. (2014) J. Infect. Dis. 209 (3), 355-359

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Immunology

NP_001166864

Q96D42

Human

MGSSHHHHHH SSGLVPRGSH MGSSVKVGGE AGPSVTLPCH YSGAVTSMCW NRGSCSLFTC QNGIVWTNGT HVTYRKDTRY KLLGDLSRRD VSLTIENTAV SDSGVYCCRV EHRGWFNDMK ITVSLEIVPP KVTTTPIVTT VPTVTTVRTS TTVPTTTTVP MTTVPTTTVP TTMSIPTTTT VLTTMTVSTT TSVPTTTSIP TTTSVPVTTT VSTFVPPMPL PRQNHEPVAT SPSSPQPAET HPTTLQGAIR REPTSSPLYS YTTDGNDTVT ESSDGLWNNN QTQLFLEHSL LTANTTKG