Recombinant humaan TIMP-1-eiwit

TIMP1, also known as TIMP metalloproteinase inhibitor 1, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Recombinant human TIPM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

TIMP metalloproteinase inhibitor 1, CLGI, EPA, EPO, HCI, TIMP

Baculovirus

Human

His-Tag

SDS-PAGE

0.2 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

21.5 kDa (190aa)

TIMP1, TIMP metalloproteinase inhibitor 1, CLGI, EPA, EPO, HCI, TIMP, ATGP3097-10 µg, ATGP3097-20 µg, ATGP3097-50 µg, ATGP3097-100 µg, ATGP3097-250 µg, ATGP3097-500 µg, ATGP3097-1 mg, ATGP3097-10, ATGP3097-20, ATGP3097-50, ATGP3097-100, ATGP3097-250, ATGP3097-500, ATGP3097-1

Ma J, et al (2013) Int J Clin Exp Pathol. 7 (1) :246-54.; ; Tarhini AA, et al (2014) J Transl Med. 12:19.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Angiogenesis

NP_003245.1

P01033

Human