Recombinant humaan TINAGL1-eiwit

TINAGL1, also known as tubulointerstitial nephritis antigen-like isoform 1, is a glycoprotein member of the peptidase C1 family of molecules. During pregnancy it binds to Laminin-1 and Integrins alpha 5 and beta 1 and plays a role in supporting fertility. In the vasculature, TINAGL1 localizes to basal laminae along adrenocortical sinusoidal capillaries where it binds to fibronectin and collagen and supports adrenocortical cell adhesion. Recombinant human TINAGL1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Tubulointerstitial nephritis antigen-like isoform 1, TINAGL1, ARG1, LCN7, LIECG3, TINAGRP

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

51.2 kDa (455aa)

TINAGL1, Tubulointerstitial nephritis antigen-like isoform 1, TINAGL1, ARG1, LCN7, LIECG3, TINAGRP, ATGP3583-10 µg, ATGP3583-20 µg, ATGP3583-50 µg, ATGP3583-100 µg, ATGP3583-250 µg, ATGP3583-500 µg, ATGP3583-1 mg, ATGP3583-10, ATGP3583-20, ATGP3583-50, ATGP3583-100, ATGP3583-250, ATGP3583-500, ATGP3583-1

Wex T. et al., (2001) Biochemistry. 40: 1350-1357.; ; Takahashi A. et al., (2016) J Reprod Dev. 62: 43-49.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Signal Transduction

NP_071447

Q9GZM7

Human

Ala

ADLAQQGRGR RELAPGLHLR GIRDAGGRYC QEQDLCCRGR ADDCALPYLG AICYCDLFCN RTVSDCCPDF WDFCLGVPPP FPPIQGCMHG GRIYPVLGTY WDNCNRCTCQ ENRQWQCDQE PCLVDPDMIK AINQGNYGWQ AGNHSAFWGM TLDEGIRYRL GTIRPSSSVM NMHEIYTVLN PGEVLPTAFE ASEKWPNLIH EPLDQGNCAG SWAFSTAAVA SDRVSIHSLG HMTPVLSPQN LLSCDTHQQQ GCRGGRLDGA WWFLRRRGVV SDHCYPFSGR ERDEAGPAPP CMMHSRAMGR GKRQATAHCP NSYVNNNDIY QVTPVYRLGS NDKEIMKELM ENGPVQALME VHEDFFLYKG GIYSHTPVSL GRPERYRRHG THSVKITGWG EETLPDGRTL KYWTAANSWG PAWGERGHFR IVRGVNECDI ESFVLGVWGR VGMEDMGHHH HHHHH