Recombinant humaan TIPIN-eiwit

TIPIN belongs to the CSM3 family. This protein is required for normal progression of S-phase and important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Recombinant human TIPIN, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

TIMELESS interacting protein, TIMELESS-interacting protein

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

36.9 kDa (324aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

TIPIN, TIMELESS interacting protein, TIMELESS-interacting protein, ATGP2342-10 µg, ATGP2342-20 µg, ATGP2342-50 µg, ATGP2342-100 µg, ATGP2342-250 µg, ATGP2342-500 µg, ATGP2342-1 mg, ATGP2342-10, ATGP2342-20, ATGP2342-50, ATGP2342-100, ATGP2342-250, ATGP2342-500, ATGP2342-1

Dheekollu, J., et al. (2011) J. Virol. 85 (12), 5853-5863; ; Kemp, M.G., et al. (2010) J. Biol. Chem. 285 (22), 16562-16571;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Epigenomics (Transcription & Translation)

NP_060328

Q9BVW5

Human

MLEPQEN GVIDLPDYEH VEDETFPPFP PPASPERQDG EGTEPDEESG NGAPVPVPPK RTVKRNIPKL DAQRLISERG LPALRHVFDK AKFKGKGHEA EDLKMLIRHM EHWAHRLFPK LQFEDFIDRV EYLGSKKEVQ TCLKRIRLDL PILHEDFVSN NDEVAENNEH DVTSTELDPF LTNLSESEMF ASELSRSLTE EQQQRIERNK QLALERRQAK LLSNSQTLGN DMLMNTPRAH TVEEVNTDED QKEESNGLNE DILDNPCNDA IANTLNEEET LLDQSFKNVQ QQLDATSRNI TEAR