Recombinant humaan TIRAP-eiwit

TIRAP (toll-interleukin1 receptor (TIR) domain containing adaptor protein) contains 1 TIR domain. This protein is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Adapter protein, TIRAP, is involved in TLR2 and TLR4 signaling pathways in the innate immune response. Recombinant human TIRAP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Toll-interleukin1 receptor (TIR) domain containing adaptor protein, BACTS1, Mal, wyatt

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

26.3 kDa (244aa) confirmed by MALDI-TOF

TIRAP, toll-interleukin1 receptor (TIR) domain containing adaptor protein, BACTS1, Mal, wyatt, ATGP1675-10 µg, ATGP1675-20 µg, ATGP1675-50 µg, ATGP1675-100 µg, ATGP1675-250 µg, ATGP1675-500 µg, ATGP1675-1 mg, ATGP1675-10, ATGP1675-20, ATGP1675-50, ATGP1675-100, ATGP1675-250, ATGP1675-500, ATGP1675-1

Semaan N., et al. (2008) J. Immunol. 180:3485-3491; ; Nagpal K., et al. (2009) J. Biol. Chem. 284:25742-25748

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,2mM DTT

Immunology

NP_001034750

P58753

Human

MGSSHHHHHH SSGLVPRGSH MGSMASSTSL PAPGSRPKKP LGKMADWFRQ TLLKKPKKRP NSPESTSSDA SQPTSQDSPL PPSLSSVTSP SLPPTHASDS GSSRWSKDYD VCVCHSEEDL VAAQDLVSYL EGSTASLRCF LQLRDATPGG AIVSELCQAL SSSHCRVLLI TPGFLQDPWC KYQMLQALTE APGAEGCTIP LLSGLSRAAY PPELRFMYYV DGRGPDGGFR QVKEAVMRYL QTLS