Recombinant humaan TMDP/DUSP13 eiwit

DUSP13 (Dual specificity phosphatase 13) belongs to the protein-tyrosine phosphatase family. It cooperates with protein kinases to regulate cell proliferation and differentiation. DUSP13 is involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. This protein exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Recombinant human DUSP13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Dual specificity protein phosphatase 13 isoform B, DUSP13B, Dual specificity phosphatase SKRP4, Testis- and skeletal-muscle-specific DSP, TMDP, muscle-restricted DUSP, BEDP, TMDP, MDSP, FLJ32450, DUSP13A

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

24.7 kDa (222aa) confirmed by MALDI-TOF

DuSP13, Dual specificity phosphatase 13, BEDP, DuSP13A, DuSP13B, MDSP, SKRP4, TMDP, ATGP1654-10 µg, ATGP1654-20 µg, ATGP1654-50 µg, ATGP1654-100 µg, ATGP1654-250 µg, ATGP1654-500 µg, ATGP1654-1 mg, ATGP1654-10, ATGP1654-20, ATGP1654-50, ATGP1654-100, ATGP1654-250, ATGP1654-500, ATGP1654-1

Chen H.-H., et al. (2004) J. Biol. Chem. 279:41404-41413; ; Katagiri C, et al. (2011) Mol Cell Biochem. 352 (1-2) :155-62.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Signal Transduction

NP_057448.3

Q9UII6

Human

MDSLQK QDLRRPKIHG AVQASPYQPP TLASLQRLLW VRQAATLNHI DEVWPSLFLG DAYAARDKSK LIQLGITHVV NAAAGKFQVD TGAKFYRGMS LEYYGIEADD NPFFDLSVYF LPVARYIRAA LSVPQGRVLV HCAMGVSRSA TLVLAFLMIC ENMTLVEAIQ TVQAHRNICP NSGFLRQLQV LDNRLGRETG RF